piet11111
19th May 2008, 16:00
http://technology.newscientist.com/article/dn13924-manmade-defensin-rips-resistant-bacteria-apart.html
In a standard measure of the risk of bacteria evolving resistance to a new treatment, the defensin outstripped conventional antibiotics.
In the test, a sample of bacteria was given enough compound to kill 90% of the culture, with the survivors used to found a new one. The process was repeated, which drives the bacteria to evolve resistance.
"For conventional antibiotics, you generally find it takes 100 times more of the antibiotic to kill the bacteria after 9 repeats," says Nick Landekic (http://www.polymedix.com/management.php), Polymedix's chief executive. "We've done 14 repeats with PMX-30063 and there is no change in its potency."
what we see here is a new type of anti-biotic that bacteria can not defend against (yet)
this is good news for humanity as drug resistant forms of normally treatable diseases are becoming more common around the world.
In a standard measure of the risk of bacteria evolving resistance to a new treatment, the defensin outstripped conventional antibiotics.
In the test, a sample of bacteria was given enough compound to kill 90% of the culture, with the survivors used to found a new one. The process was repeated, which drives the bacteria to evolve resistance.
"For conventional antibiotics, you generally find it takes 100 times more of the antibiotic to kill the bacteria after 9 repeats," says Nick Landekic (http://www.polymedix.com/management.php), Polymedix's chief executive. "We've done 14 repeats with PMX-30063 and there is no change in its potency."
what we see here is a new type of anti-biotic that bacteria can not defend against (yet)
this is good news for humanity as drug resistant forms of normally treatable diseases are becoming more common around the world.