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View Full Version : stomach proof gel to replace insuline injections



piet11111
22nd April 2008, 23:11
http://technology.newscientist.com/article/dn13751-stomachproof-gel-hints-at-jabfree-diabetes-treatment.html


A gel that can smuggle insulin past the stomach and slowly release the drug into the blood could do away with diabetics' daily injections.
Pills made from the new material could also deliver other protein-based drugs, such as human growth hormone, that must be protected from being digested in the stomach.
"A big difficulty with type I diabetes (http://en.wikipedia.org/wiki/Type_I_diabetes) is insulin must be [injected] two to three times a day," says Nicholas Peppas (http://www.engr.utexas.edu/che/directories/faculty/peppas.cfm) of the University of Texas at Austin, US.
Researchers and drug companies have for years searched for an easier way to deliver insulin to avoid the pain and bruising that regular injections can cause. Cheek patches and insulin inhalers have both been investigated, but both have so far failed to make it onto the market.


if this works it would be great news for people that have to use insulin injections.
and as a diabetic myself (i dont need injections fortunately) i was fearing the possibility that if i get old and the diabetes got worse i would be forced to use injections (vaccinations in school with a trainee doctor you know how that goes) but now i need not fear my nightmare scenario

Bluetongue
29th April 2008, 23:41
Injecting insulin isn't really a huge trauma. I do it once a day. Still, a pill would be nice.

Dean
1st May 2008, 05:46
http://technology.newscientist.com/article/dn13751-stomachproof-gel-hints-at-jabfree-diabetes-treatment.html



if this works it would be great news for people that have to use insulin injections.
and as a diabetic myself (i dont need injections fortunately) i was fearing the possibility that if i get old and the diabetes got worse i would be forced to use injections (vaccinations in school with a trainee doctor you know how that goes) but now i need not fear my nightmare scenario

Let's hope it is adequately tested before an unknowing consumer base is used as a de facto test group.

anarchista feminista
1st May 2008, 09:57
ah personally if i had diabetes i would prefer injections. i have difficulty swallowing tablets. i have a strange fear of choking or not being able to breathe. but it's good to see there will be an alternative. my cousin has had to get that machine you wear that automatically gives you your dosage every day.

anarchista feminista
8th May 2008, 09:26
Hmmm. Pigs to cure diabetes?
www.abc.net.au/news/stories/2007/08/30/2019096.htm (http://www.revleft.com/vb/www.abc.net.au/news/stories/2007/08/30/2019096.htm)

piet11111
8th May 2008, 11:46
Hmmm. Pigs to cure diabetes?
www.abc.net.au/news/stories/2007/08/30/2019096.htm (http://www.revleft.com/vb/www.abc.net.au/news/stories/2007/08/30/2019096.htm)

cool seems pigs are rapidly replacing dogs as mans best friend :D

anarchista feminista
8th May 2008, 12:29
On Channel Ten news I heard about it, and apparently they've been studying it for quite some time. Then the presenter actually said something along the lines of "Maybe now pigs can have a purpose other than bacon". HOW AWFUL!

Mujer Libre
8th May 2008, 15:27
This is an interesting development considering the relative failure of inhaled insulin to replace injections at mealtimes.

However, one of the big advantages of injected insulins (particularly Novorapid) at mealtimes for type 1 diabetics is that it acts almost instantaneously and therefore allows for a lot of flexibility in meals and physical activity. If this pill needs to be broken down in the stomach, there will be a delay in its action- maybe 20-30mins? This takes away some of the flexibility and potential for tight glycaemic control that people on a basal bolus regimen have.

piet11111
8th May 2008, 18:51
This is an interesting development considering the relative failure of inhaled insulin to replace injections at mealtimes.

However, one of the big advantages of injected insulins (particularly Novorapid) at mealtimes for type 1 diabetics is that it acts almost instantaneously and therefore allows for a lot of flexibility in meals and physical activity. If this pill needs to be broken down in the stomach, there will be a delay in its action- maybe 20-30mins? This takes away some of the flexibility and potential for tight glycaemic control that people on a basal bolus regimen have.

this pill will be broken down in the gut instead of the stomach.


the presenter actually said something along the lines of "Maybe now pigs can have a purpose other than bacon". HOW AWFUL!

that is horrible ! pig's meat can be used in so many diverse ways other then bacon :crying:

Mujer Libre
9th May 2008, 07:14
this pill will be broken down in the gut instead of the stomach.
That's even worse, considering the transit time!