Ketamine relieves depression symptoms within hours

[Os Cangaceiros]

Small amounts of the drug ketamine can immediately relieve the symptoms of chronic depression, as well as those of treatment-resistant patients within a few hours, say Yale scientists.

After a decades' worth of research, experts from Yale School of Medicine suggest in the journal Science that the pediatric anesthetic repairs synaptic connections between brain cells that have been impaired by depression (http://www.medicalnewstoday.com/articles/8933.php) and stress (http://www.medicalnewstoday.com/articles/145855.php).

http://www.medicalnewstoday.com/articles/251220.php

[Ostrinski]

How easy is this to get? I might need to take note of this.

[The Douche]

Drugs make you happy? Fucking scientific breakthrough right there, I'll tell you what...

[PC LOAD LETTER]

How easy is this to get? I might need to take note of this.
There are markets on tor with reputation systems for sellers. The most famous one being named after a historical trade route system between Europe and East Asia

[Os Cangaceiros]

Drugs make you happy? Fucking scientific breakthrough right there, I'll tell you what...

The news report that I heard about this made it sound a lot more significant than just that. (If you weren't just being sarcastic...)

This hasn't been released to the public yet, but based on some of the clinical studies they've done, it could be more effective at treating chemical depression than some of the earlier drugs...the last unique medication released that targeted depression was released decades ago. (IIRC it was Prozac)

[Yuppie Grinder]

Ket is something you wanna be really careful with. Can be addictive.

[Rusty Shackleford]

There are markets on tor with reputation systems for sellers. The most famous one being named after a historical trade route system between Europe and East Asia
id be suuuuuuuper wary of using something like that.


and before you ask, no i have no recommendations on how to get it.

[ВАЛТЕР]

I'm not a fan of drugs, but recently I got diagnosed with chronic depression, so now I'm on that Zoloft to keep from killin' ya'll...

[Leonid Brozhnev]

My mum's been taking the stuff for years as pain relief medication, and as an alternative to morphine after she'd built up a tolerance. So yeah, I imagine taking tranquilisers would make you feel less depressed very quickly.
She's crazy, but it's hard to tell if that was the ketamine or not since she's been on every pain relief drug known to man.

[Quail]

Ket is something you wanna be really careful with. Can be addictive.
The psychological aspect of ketamine addiction could very easily be related to its depression-alleviating properties.

[Kenco Smooth]

Not kept a close eye on it but I know there was a fair bit of skepticism surrounding the Ketamine trials a while back. Namely that if one group gets a placebo and the other gets ketamine you can be pretty sure they're going to notice the difference.

[Dennis the 'Bloody Peasant']

Whenever I hear about this drug I think of a quote from Series 3 of The Thick of It

Glenn: "Would you like a cup of tea?"
Nicola Murray MP: "No! Get me some ketamine; I want to seperate my mind from my body"

[Comrade #138672]

I've also heard that it can improve your cognitive abilities, but yeah, you should be very careful with it and not become a passive drug addict.

[Manic Impressive]

I'm massively skeptical about this having had a lot of experience with ketamine in my youth. Not least because of the psychedelic effects. It can easily result in bad trips. Also paranoia although I also disagree about the implied addictiveness. Frankly it's incomparable to cocaine, heroin, alcohol or nicotine on that front, I'd even argue that caffeine can be more addictive. As for improving cognitive abilities the opposite seems more likely.

I don't want to go into too much detail about my dealings with it but lets just say I used to acquire it by the litre.

[Sasha]

How easy is this to get? I might need to take note of this.

Its a pretty commonly available drug since its in large doses its the only available anesthetic that doesnt impede your breathing, which means you don't need to intubate patients (which can be dangerous for your vocal cords etc) so its used a lot by pediatricians and veterinarians.
But like any drug, if you are not using it recreational get a professional doctor involved.
The dose (and kind) of amphetamins I take for my ADD is completely different than what I used to take recreationally. (though the biggest danger with ket is in its addiction and traffic/machinery/tools dangers, as long as you don't mix it with other stuff its pretty hard to o.d. on exactly because its unique "not messing with your respiratorysystem" properties, its fucking scary though as its a dissociative, i.e. it shuts down your body while your mind, hearing, sight etc is still working, you get temporary "locked in" so to speak)

[leaveuskidsalone]

Ketamine also drags you into a world where you don't feel and happily snort more ketamine as long as it keeps you from coming to terms with your normal every day-to-day problems. :rolleyes:

I'm not straight edge or anything, I even did ketamine last weekend, but I honestly don't believe that most drugs have any healthy benefits to them (save maybe LSD and shrooms).

[Os Cangaceiros]

I just don't understand how the possibility that a drug could be abused totally negates any possible medical benefits it may possess...:confused:

It's like people just see the word "ketamine" and start saying "OOOOOOOHHHHHHH don't fuck with that shit, man, I used to buy that shit on the street corner, don't do it brah!"

[doesn't even make sense]

I just don't understand how the possibility that a drug could be abused totally negates any possible medical benefits it may possess...:confused:

It's like people just see the word "ketamine" and start saying "OOOOOOOHHHHHHH don't fuck with that shit, man, I used to buy that shit on the street corner, don't do it brah!"

Yeah, they're talking small doses here, so I'm assuming way below any recreational or even serious anesthetic dose. And they're reporting that it causes observable improvements in the brain, it's not just based on people's reports of how they feel after taking it.

I recall reading a story from google news sometime in the past couple of months about a new drug they were testing with similarities to opiates sans the high that also seemed to have dramatically positive effects on depression.

[Sasha]

The interesting thing with ket is that it seems to rewire/reboot the neurological connections in your brain, which makes it now a major field of intrest for alzheimer and dementia treatment.
In other words its neurological properties are more in the field of mdma etc than of opiates, something the scientific community would never had considerd if it wasn't adopted in low doses as a recreational drug, in high medicinal doses it was just considered a quirky anesthetic that gave a good solution for anestisising kids and small mammals that you could not intubate.

[Os Cangaceiros]

update on ketamine depression research

http://www.bbc.com/news/health-26647738

[tallguy]

I'm not a fan of drugs, but recently I got diagnosed with chronic depression, so now I'm on that Zoloft to keep from killin' ya'll...
:lol:

Good man

[Sasha]

Anyone linked this one already?
http://m.vice.com/read/ketamine-fixed-me

[Sea]

Actually, when taken intramuscularly it relieves the symptoms of depression within minutes, not hours.

[victorcast]

There seem to be far to many people here who seem to think that ketamine used to treat depression is either for veterinary use, unregulated quality and/or in doses strong enough to kill you.

[Luís Henrique]

Ket is something you wanna be really careful with. Can be addictive.

It is also an anaesthesic used in veterinary.

The reason it isn't used in humans is that it can cause amnesia, which isn't a problem in animals.

Luís Henrique

[Sasha]

it is used on humans, most notably on children because its the only anesthetic that doesnt stop the breathing functions so you dont have to intubate during the medical procedures (intubating can be very dangerous for children because it can easily damage a.o. their vocal cords), its used on small animals for the same reasons.
which is also the main reason its pretty hard to OD on.
the reason it isnt used that much on adults as an anesthetic is just that for them there are enough alternatives that come with less side effects (for one the intense dissociative experience that happens in large doses can be pretty scary).
the amnesia is not something i heard much about, in my experience that is more a side effect of GHB.

[Os Cangaceiros]

There are drugs used in humans that do commonly cause anterograde amnesia, most notably benzodiazepines.